DIAGNOSTIC SERVICES
Next Generation Sequencing
Turnaround time: 3-5 days
Hematology Panels
Comprehensive Myeloid Panel
Our comprehensive myeloid NGS panel streamlines the analysis of hematologic malignancies by consolidating multiple complex tests into a single, targeted assay. This panel delivers broad and clinically relevant coverage of the key genetic alterations driving myeloid disorders.
With a total of 69 target genes (comprising 40 key DNA target genes and 29 critical driver genes within a broad fusion panel) the assay enables sensitive detection of DNA mutations, insertions/deletions, and fusion transcripts at a limit of detection as low as 3%. This powerful approach reduces turnaround time, increases efficiency, and provides deeper insights into the molecular drivers of disease.
Diseases covered include:
- Acute Myeloid Leukemia (AML)
- Myelodysplastic Syndromes (MDS)
- Myeloproliferative Neoplasms (MPN)
- Chronic Myeloid Leukemia (CML)
- Chronic Myelomonocytic Leukemia (CMML)
- Juvenile Myelomonocytic Leukemia (JMML)
- Mast Cell Leukemia
| Hotspot genes (23) | Full genes (17) | Fusion driver genes (29) | Expression genes (5) | Expression control genes (5) | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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Comprehensive Lymphoid Panel
Our lymphoid NGS panel delivers comprehensive profiling across 66 lymphoma-associated genes. This design enables sensitive detection of clinically significant mutations, insertions/deletions, and splice-site variants with a variant allele frequency (VAF) threshold of 3%.
The panel addresses the complexity and heterogeneity of lymphoid neoplasms in a single, streamlined assay, eliminating the need for multiple sequential tests. It provides broad molecular insights that support diagnosis, prognostic stratification, and therapeutic decision-making, while also aligning with NCCN and WHO guidelines.
Diseases covered include:
- Chronic Lymphocytic Leukemia (CLL)
- Marginal Zone Lymphoma
- Lymphoplasmacytic Lymphoma (LPL)
- Follicular Lymphoma (FL)
- Mantle Cell Lymphoma (MCL)
- Hairy Cell Leukemia
- Diffuse Large B-Cell Lymphoma (DLBCL)
- Other Lymphoid Neoplasms
| Full Genes |
| ATM |
| CREBBP |
| KMT2D |
| NOTCH1 |
| TP53 |
| Hotspot | |||||
| ARID1A | DDX3X | JAK2 | NRAS | SETD2 | XPO1 |
| B2M | DNMT3A | JAK3 | PAX5 | SF3B1 | |
| BCL2 | EP300 | KLF2 | PHF6 | SGK1 | |
| BIRC3 | EZH2 | KMT2C | PIK3CA | SOCS1 | |
| BRAF | FBXW7 | KRAS | PIM1 | SPEN | |
| BTK | FOXO1 | MAP2K1 | PLCG2 | STAT3 | |
| CARD11 | GNA13 | MEF2B | PRDM1 | STAT5B | |
| CD79B | ID3 | MTOR | PTEN | STAT6 | |
| CDKN1B | IDH1 | MYC | PTPN11 | TCF3 | |
| CDKN2A | IDH2 | MYD88 | PTPRD | TET2 | |
| CIITA | IRF4 | NF1 | RB1 | TNFAIP3 | |
| CXCR4 | JAK1 | NOTCH2 | RHOA | NFRSF14 | |
Solid Tumor Panels
Solid Tumor Gene Panel
Our Oncomine Focus Assay (OFA) is a targeted next-generation sequencing (NGS) panel designed to detect the most clinically relevant genomic alterations across a wide range of solid tumors. This assay consolidates multiple testing methods into a single, streamlined workflow, providing fast and comprehensive insights to support precision oncology.
The OFA interrogates 52 key cancer driver genes, covering the most common classes of alterations, including hotspot mutations, copy number variations (CNVs), and gene fusions. This broad profiling allows simultaneous detection of actionable biomarkers with high sensitivity using limited FFPE tissue samples.
| Hotspot Genes (35 Genes) | |
| AKI1 | IDH2 |
| ALK | JAKI |
| AR | JAK1 |
| BRAF | JAK2 |
| CDK4 | JAK3 |
| CTNNB1 | KIT |
| DDR2 | KRAS |
| EGFR | MAP2K1 |
| ERBB2 | MAP2K2 |
| ERBB3 | MET |
| ERBB4 | MTOR |
| ESR1 | NRAS |
| FGFR2 | PDGFRA |
| FGFR3 | PIK3CA |
| GNA11 | RAF1 |
| GIVAQ | RET |
| HRAS | ROS1 |
| IDH1 | SMO |
| Copy Number Genes (19 Genes) | |
| AKT1 | FGFR2 |
| ALK | FGFR3 |
| AR | FGFR4 |
| BRAF | KIT |
| CCNDI | KRAS |
| CDK4 | MET |
| CDK6 | MYC |
| EGFR | MYCN |
| ERBB2 | PDGFRA |
| FGFR1 | PIK3CA |
| Gene Fusions (23 Genes) | |
| ABL1 | FGFR2 |
| AKT3 | FGFR3 |
| ALK | MET |
| AXL | NTRK1 |
| BRAF | NTRK2 |
| EGER | NTRK3 |
| ERBB2 | PDGFRA |
| ERG | PPARG |
| ETV1 | RAF1 |
| ETV4 | RET |
| ETV5 | ROS1 |
| FGFR1 | |
Tumor Specific Panels
| Colorectal Panel (14 GENES) | |||||
| AKT1 | BRAF | EGFR | ERBB2 | ERBB4 | FGFR2 |
| FGFR3 | HRAS | KRAS | MET | MAP2K1 | NRAS |
| NTRK1 | PIK3CA | ||||
| Gynecologic Panel (12 GENES) | |||||
| AKT1 | BRAF | AR | EGFR | ERBB2 | ESR1 |
| FGFR1 | FGFR2 | KRAS | MYC | NTRK1 | PIK3CA |
| Melanoma Panel (12 GENES) | ||||||
| BRAF | CDK4 | CTNNB1 | GNA11 | GNAQ | KIT | MAP2K1 |
| NRAS | NTRK1 | PDGFRA | PIK3CA | SMO | ||
| Lung Panel (13 GENES) | ||||||||
| ATK1 | ALK | BRAF | DDR2 | EGFR | ERBB2 | FGFR1 | KRAS | MAP2K1 |
| MET | NRAS | NTRK1 | PIK3CA | |||||
| Urologic Panel (7 GENES) | |||||
| AR | ERG | ETV1 | ETV4 | MYC | NTRK1 |
| PALB2 | |||||












