DIAGNOSTIC SERVICES
Molecular- Solid Tumor
The Solid Tumor NGS test at Cairo diagnostics analyzes over 1,000 biomarkers across 52 genes. It detects relevant hotspots, SNVs, indels, CNVs, and gene fusions using a single workflow for DNA and RNA. It enables detection of NTRK1, NTRK2, and NTRK3 gene fusion. Includes solid tumor genes for 23 different types of cancer targeted by on-market oncology drugs and published evidence. It contains 7 genes on 43 labels, 15 genes in 19 guidelines and 43 genes in >900 global clinical trials.
Oncomine Focus Gene Panel
| Hotspot Genes (35 Genes) | |||
| AKT1 | IDH2 | ||
| ALK | JAKI | ||
| AR | JAK1 | ||
| BRAF | JAK2 | ||
| CDK4 | JAK3 | ||
| CTNNB1 | KIT | ||
| DDR2 | KRAS | ||
| EGFR | MAP2K1 | ||
| ERBB2 | MAP2K2 | ||
| ERBB3 | MET | ||
| ERBB4 | MTOR | ||
| ESR1 | NRAS | ||
| FGFR2 | PDGFRA | ||
| FGFR3 | PIK3CA | ||
| GNA11 | RAF1 | ||
| GIVAQ | RET | ||
| HRAS | ROS1 | ||
| IDH1 | SMO | ||
| Copy Number Genes (19 Genes) | |||
| AKT1 | FGFR2 | ||
| ALK | FGFR3 | ||
| AR | FGFR4 | ||
| BRAF | KIT | ||
| CCNDI | KRAS | ||
| CDK4 | MET | ||
| CDK6 | MYC | ||
| EGFR | MYCN | ||
| ERBB2 | PDGFRA | ||
| FGFR1 | PIK3CA | ||
| Gene Fusions (23 Genes) | |||
| ABL1 | FGFR2 | ||
| AKT3 | FGFR3 | ||
| ALK | MET | ||
| AXL | NTRK1 | ||
| BRAF | NTRK2 | ||
| EGER | NTRK3 | ||
| ERBB2 | PDGFRA | ||
| ERG | PPARG | ||
| ETV1 | RAF1 | ||
| ETV4 | RET | ||
| ETV5 | ROS1 | ||
| FGFR1 | |||
Tumor Specific Panels
| Colorectal Panel (14 Genes) | |||||||
| AKT1 | BRAF | EGFR | ERBB2 | ERBB4 | FGFR2 | ||
| FGFR3 | HRAS | KRAS | MET | MAP2K1 | NRAS | ||
| NTRK1 | PIK3CA | ||||||
| Gynecologic Panel (12 Genes) | |||||||
| AKT1 | BRAF | AR | EGFR | ERBB2 | ESR1 | ||
| FGFR1 | FGFR2 | KRAS | MYC | NTRK1 | PIK3CA | ||
| Melanoma Panel (12 Genes) | ||||||||
| BRAF | CDK4 | CTNNB1 | GNA11 | GNAQ | KIT | MAP2K1 | ||
| NRAS | NTRK1 | PDGFRA | PIK3CA | SMO | ||||
| Lung Panel (13 Genes) | ||||||||||
| ATK1 | ALK | BRAF | DDR2 | EGFR | ERBB2 | FGFR1 | KRAS | MAP2K1 | ||
| MET | NRAS | NTRK1 | PIK3CA | |||||||
| Urologic Panel (12 Genes) | |||||||
| AR | ERG | ETV1 | ETV4 | MYC | NTRK1 | ||
| PALB2 | |||||||